68329:HUMAN PAPILLOMA VIRUS (HPV) DNA PROBE, HIGH RISK GROUP ONLY
Methodology:
Nucleic Acid Probe; Hybrid Capture
Edit Date:
5/15/2010
Performed:
Monday, Wednesday, Thursday, Friday
Released:
2-4 days
CPT Code:
87621
Specimen Collection Details
Collection:
Cervical or endocervical sample using the TRIPATH (SurePath) Liquid-based Pap Smear Preservation Fluid OR cervical brush used with the Digene hc2 DNA Collection Device containing cervical brush and specimen transport medium. Also acceptable: cervical brush in THIN PREP Pap Fixative.
Stability:
TRIPATH (SurePath) Preservation Fluid: 4 weeks ambient. Digene hc2 DNA Collection Device submitted in transport medium: 2 weeks ambient, 3 weeks refrigerated, or 3 months frozen. THIN PREP Pap Fixative: 3 weeks ambient.
Minimum Volume:
SurePath 2 mL; ThinPrep 4 mL.
Transport:
Ambient or refrigerated.
Comments:
Specific HPV genotypes have been shown to be associated with certain anogenital diseases. Types 16, 18, 31, 33, 35, 39, 45, and 51, 52, 56, 58, 59 and 68 (high risk group) are associated with cervical carcinoma and its predisposing lesions, cervical atypia, severe dysplasia, cervical intraepithelial neoplasia (CIN) and carcinoma in situ. Note: a negative result does not rule out the presence of another HPV genotype not in the test panel, nor one of the panel types missed because of low level infection or specimen sampling error. Results will be reported by group assay only.
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