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90885:WEST NILE VIRUS ANTIBODY PANEL, SERUM
Methodology:Enzyme-Linked Immunosorbent Assay (ELISA)
Edit Date:1/4/2007
Performed:Tuesday, Friday
Released:1-8 days after setup at PeaceHealth Laboratories’ reference lab.
CPT Code:86788-90 / 86789-90
Specimen Collection Details
Collection:One 7.5 mL serum separator tube (SST).
Handling:Allow to clot, centrifuge and separate serum from cells and pour into plastic vial. Refrigerate.
Stability:Specimen stable 48 hours ambient, 14 days refrigerated, or 1 year frozen.
Standard Volume:1 mL serum.
Minimum Volume:0.5 mL serum.
Transport:Refrigerated.
Comments:This test is intended to be used as a semi-quantitative means of detecting West Nile virus-specific IgG and IgM in serum samples in which there is a clinical suspicion of West Nile virus infection. This test should not be used solely for quantitative purposes, nor should the results be used without correlation to clinical history or other data. Because other members of the Flaviviridae family, such as St. Louis encephalitis virus, show extensive cross-reactivity with West Nile virus, serologic testing specific for these species should also be performed.
Rejection Criteria:Plasma; lipemic, hemolyzed, contaminated, or heat-inactivated specimen.
Reference Range:
West Nile Virus Antibody, IgG by ELISA, Serum
<1.30 IV Negative No significant level of West Nile virus IgG antibody detected.
1.30-1.50 IV Equivocal Questionable presence of West Nile virus IgG antibody detected. Repeat testing in 10-14 days may be helpful.
>1.50 IV Positive Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.
West Nile Virus Antibody, IgM by ELISA, Serum
<.90 IV Negative No significant level of West Nile virus IgM antibody detected.
0.90-1.10 IV Equivocal Questionable presence of West Nile virus IgM antibody detected. Repeat testing in 10-14 days may be helpful.
>1.10 IV Positive Presence of IgM antibody to West Nile virus detected, suggestive of current or past infection.