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Alias Names: Zoloft
Methodology: Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Edit Date: 11/16/2009
Performed: Tuesday, Friday
Released: 1-5 days after setup at PeaceHealth Laboratories’ reference lab
CPT Code: 80299-90
Specimen Collection Details
Collection: One 5 mL red top tube. Also acceptable: One 4 mL lavender top tube (EDTA), 4 mL green top tube (sodium heparin), or 4 mL grey top tube (sodium fluoride/potassium oxalate). Do not use gel separator tubes (SST or PST).
Handling: Allow to clot, centrifuge and separate serum or plasma from cells into a plastic vial.
Stability: Specimen stable 12 hours ambient, 4 days refrigerated, or 30 days frozen.
Standard Volume: 2 mL serum or plasma.
Minimum Volume: 1.5 mL serum or plasma.
Transport: Refrigerated.
Rejection Criteria: Use of SST or PST.
This test may require insurance company prior authorization before ordering.
Please check the prior authorization list
Failure to gain preauthorization may result in denial of coverage.

Reference Range:
Therapeutic Range
Not well established.
Interpretive Data
No therapeutic range exists for Sertraline. Dosing should begin at 50 mg/d, not to exceed 200 mg/d. Dosing above 200 mg/d is associated with increased adverse effects and decreased efficacy. Dosing of 50-200 mg/d gives serum values ranging from 30-200 ng/mL.

PeaceHealth Laboratories