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| 89700:SERTRALINE (ZOLOFT) | |||||||||
| Alias Names: | Zoloft | ||||||||
| Methodology: | Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) | ||||||||
| Edit Date: | 11/16/2009 | ||||||||
| Performed: | Tuesday, Friday | ||||||||
| Released: | 1-5 days after setup at PeaceHealth Laboratories’ reference lab | ||||||||
| CPT Code: | 80299-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | One 5 mL red top tube. Also acceptable: One 4 mL lavender top tube (EDTA), 4 mL green top tube (sodium heparin), or 4 mL grey top tube (sodium fluoride/potassium oxalate). Do not use gel separator tubes (SST or PST). | ||||||||
| Handling: | Allow to clot, centrifuge and separate serum or plasma from cells into a plastic vial. | ||||||||
| Stability: | Specimen stable 12 hours ambient, 4 days refrigerated, or 30 days frozen. | ||||||||
| Standard Volume: | 2 mL serum or plasma. | ||||||||
| Minimum Volume: | 1.5 mL serum or plasma. | ||||||||
| Transport: | Refrigerated. | ||||||||
| Rejection Criteria: | Use of SST or PST.
This test may require insurance company prior authorization before ordering.
Please check the prior authorization list . Failure to gain preauthorization may result in denial of coverage. |
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| Reference Range: | |||||||||||||||||||
| Therapeutic Range |
Not well established.
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| Interpretive Data |
No therapeutic range exists for Sertraline. Dosing should begin at 50 mg/d, not to exceed 200 mg/d. Dosing above 200 mg/d is associated with increased adverse effects and decreased efficacy. Dosing of 50-200 mg/d gives serum values ranging from 30-200 ng/mL.
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