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|70091:HUMAN PAPILLOMA VIRUS (HPV) WITH DNA PROBE AND SUREPATH PAP (30 YEARS AND OLDER)|
|Alias Names:||Cytopathology, LB, PAP/DNA Probe and HPV >30 YO / PAP, LB, HPV/DNA Probe >30 YO|
|Methodology:||Nucleic Acid Probe / Hybrid Capture / Bethesda Reporting System|
|CPT Code:||88142 / 87621|
|Specimen Collection Details|
|Collection:||Contraindications: Rover Cervex Brush is not to be used on patients after the first 10 weeks of pregnancy. Cytobrush and Spatula are not to be used on pregnant patients. Do not use Cytobrush for endometrial sampling.
Collect cervical or endocervical specimen with a Rover Cervex brush, rotating clockwise 5 times. Snap the brush tip into SurePath vial and tighten cap. Alternatively, cervical or endocervical specimen can be collected using plastic spatula and cytobrush. Select contoured end of spatula and rotate 360° around entire exocervix while maintaining tight contact with exocervical surface. Snap contoured end of spatula into SurePath vial. Insert cytobrush into endocervix until only bottom-most bristles are exposed at the outside. Slowly rotate ¼ to ½ turn in one direction. Do not over-rotate. Snap cytobrush into SurePath vial and tighten cap.
|Handling:||Label SurePath vial with patient name and physician name.|
|Stability:||Specimen in SurePath Preservative Fluid stable 4 weeks ambient.|
|Comments:||Specific HPV genotypes have been shown to be associated with certain anogenital diseases. Types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68 (high risk groups) are associated with cervical carcinoma and its predisposing lesions, cervical atypia, severe dysplasia, cervical intraepithelial neoplasia (CIN) and carcinoma in situ. Note: A negative result does not rule out the presence of another HPV genotype not in the test panel, nor one of the panel types missed because of low-level infection or specimen sampling error.|
|Rejection Criteria:||SurePath vial past expiration date; no specimen collected; unlabeled or mislabeled specimen.|