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|70066:CYTOPATHOLOGY, THINPREP™ PAP WITH HPV (30 YEARS AND OLDER)|
|Alias Names:||Thin Prep|
|Methodology:||Bethesda Reporting System. Screening done under pathologist’s supervision.|
|Released:||2-4 days, weekdays|
|CPT Code:||88142 / 87621|
|Specimen Collection Details|
|Collection:||Contraindications: Papette is not to be used on patients after first 10 weeks of pregnancy. Spatula and Cytobrush: Do not use cytobrush on pregnant patient or for endometrial sampling.
Collect cervical or endocervical specimen with a Papette brush, rotating brush 5 times in either direction. Rinse brush in ThinPrep vial by pushing the brush into the bottom of the vial 10 times, forcing the bristles apart. Swirl the brush vigorously to further release material. Discard the collection device and tighten vial cap so torque line on cap passes torque line on vial. Alternatively, cervical or endocervical specimen can be collected using spatula and cytobrush. Select contoured end of plastic spatula and rotate 360° around entire exocervix while maintaining tight contact with exocervical surface. Rinse contoured end of spatula in ThinPrep vial by swirling vigorously 10 times. Discard spatula. Cap vial. Insert cytobrush into the endocervix until only the bottom-most bristles are exposed at the outside. Slowly rotate ¼ to ½ turn in one direction. Do not over–rotate. Rinse the cytobrush in the ThinPrep vial by rotating the device in the solution 10 times while pushing it against the wall of the vial. Swirl the device vigorously to further release material. Discard cytobrush. Tighten vial cap so torque line on cap passes torque line on vial. Note: Do not leave collection devices in the ThinPrep vial.
|Handling:||Label ThinPrep vial with patient name and physician name.|
|Comments:||Specific HPV genotypes have been shown to be associated with certain anogenital diseases. Types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68 (high risk group) are associated with cervical carcinoma and its predisposing lesions, cervical atypia, severe dysplasia, cervical intraepithelial neoplasia (CIN), and carcinoma in situ. Note: A negative result does not rule out the presence of another HPV genotype not in the test panel, nor one of the panel types missed because of low-level infection or specimen sampling error.|
|Rejection Criteria:||ThinPrep vial past expiration date; no specimen collected; unlabeled or mislabeled specimen.|