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Alias Names: Wellbutrin® / Zyban®
Methodology: High-Performance Liquid Chromatography (HPLC)
Edit Date: 6/11/2010
Performed: Monday, Thursday
Released: 1-5 days after setup at PeaceHealth Laboratories’ reference lab.
CPT Code: 80299-90
Specimen Collection Details
Collection: One 5 mL red top tube. Do not use serum separator tube (SST) or plasma separator tube (PST. Also acceptable: One 4 mL lavender top tube (EDTA), 4 mL green top tube (sodium heparin), or 4 mL grey top tube (sodium fluoride/potassium oxalate).
Handling: Allow to clot, centrifuge and separate serum or plasma from cells into a plastic vial. Freeze within 2 hours of collection. Critical frozen. Send separate specimen if multiple tests are ordered.
Stability: 30 days frozen. Unstable ambient or refrigerated.
Standard Volume: 2.5 mL serum or plasma.
Minimum Volume: 1.5 mL serum or plasma.
Transport: Frozen, on dry ice.
Rejection Criteria: Use of SST or PST; thawed, ambient, or refrigerated specimen.
This test may require insurance company prior authorization before ordering.
Please check the prior authorization list
Failure to gain preauthorization may result in denial of coverage.

The therapeutic range is not well established. Patient response appears to improve with concentrations between 50 and 100 ng/mL. Levels below 25 ng/mL may have no effect. Poor response and increased toxicity have been reported at concentrations above 100 ng/mL.

PeaceHealth Laboratories