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| 91689:MYELOPEROXIDASE ANTIBODY | |||||||||
| Alias Names: | MPO Ab | ||||||||
| Methodology: | Multi-Analyte Fluorescent Detection | ||||||||
| Edit Date: | 1/1/2009 | ||||||||
| Performed: | Daily | ||||||||
| Released: | 24-48 hours after setup at PeaceHealth Laboratories’ reference lab | ||||||||
| CPT Code: | 83516-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | One 7.5 mL serum separator tube (SST). | ||||||||
| Handling: | Centrifuge and separate serum from cells immediately and pour into a plastic vial. Refrigerate. | ||||||||
| Stability: | 48 hours ambient, 14 days refrigerated, or 1 year frozen. Allow no more than one freeze/thaw cycle. | ||||||||
| Standard Volume: | 1 mL serum. | ||||||||
| Minimum Volume: | 0.5 mL serum. | ||||||||
| Transport: | Refrigerated. | ||||||||
| Rejection Criteria: | Plasma; urine, or other body fluids; severely lipemic, contaminated, or hemolyzed specimens. | ||||||||
| Reference Range: | |||||||||||||||||||
| ≤ 19 AU/mL |
Negative
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| 20-25 AU/mL |
Equivocal
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| ≥ 26 AU/mL |
Positive
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| Approximately 90% of patients with a P-ANCA pattern by IFA have antibodies specific for MPO.
Approximately 85% of patients with a C-ANCA pattern by IFA have antibodies specific for PR3. |
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