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| 90380:IODINE, FREE, URINE | |||||||||
| Alias Names: | Iodide Excretion | ||||||||
| Methodology: | Inductively Coupled Plasma/Mass Spectrometry (ICP/MS) | ||||||||
| Edit Date: | 6/8/2009 | ||||||||
| Performed: | Wednesday | ||||||||
| Released: | 24 hours after setup at reference lab. | ||||||||
| CPT Code: | 83789-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | 24-hour urine in a clean, dry plastic container. Refrigerate during collection, storage, and transport. NOTE: If this test is used in conjunction with the 131I uptake test, the patient should void and discard the urine just prior to the 131I, and all subsequent urine should be collected for the next 24 hours. The last void should be included in the collection. Refrigeration is preferred. 50% Acetic Acid is acceptable when specimen will be collected for other tests that require it. | ||||||||
| Handling: | Aliquot 50 mL from the 24-hour collection in a plastic bottle and refrigerate. Total volume of 24-hour collection is required. | ||||||||
| Stability: | Unstable frozen. | ||||||||
| Standard Volume: | 50 mL urine aliquot. | ||||||||
| Minimum Volume: | 1 mL urine aliquot. | ||||||||
| Transport: | Refrigerated. | ||||||||
| Comments: | This assay measures only the free or ionized form of iodine; organic iodine found in drugs or other compounds is not measured. Useful for monitoring iodine excretion rate as an index of daily iodine replacement therapy. | ||||||||
| Rejection Criteria: | Preservatives other than Acetic Acid. | ||||||||
| Reference Range: | |||||||||||||||||||
| 100-460 µg/specimen |
Daily urinary output <100 µg/specimen suggests dietary deficiency.
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Values >460 µg/specimen may indicate dietary excess, but more frequently suggest recent drug or contrast media exposure.
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| 42-350 µg/L (random collection) | |||||||||||||||||||
| Administration of iodine-based contrast media and drugs containing iodine, such as amiodarone, will yield elevated results.
If gadolinium-containing contrast media has been administered, a specimen should not be collected for 48 hours. |
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