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| 82470:CRYOGLOBULINS, QUANTITATIVE | |||||||||
| Methodology: | Agarose Electrophoresis (AE) / Inspection (Insp) / Nephelometry (NEPH) | ||||||||
| Edit Date: | 1/26/2010 | ||||||||
| Components: | Cryoglobulin 72 hours / Cryoglobulin 7 days / Cryoprecipitate IgG / Cryoprecipitate IgM / Cryoprecipitate IgA / Cryoprecipitate RF / IFE on Cryoprecipitate | ||||||||
| Performed: | Monday-Saturday | ||||||||
| Released: | 7 days after setup at PeaceHealth Laboratories reference lab | ||||||||
| CPT Code: | 82595-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | Two 5 mL red top tubes which have been pre-warmed to 37° C. Patient must be fasting. NOTE: Do not collect on a Friday. | ||||||||
| Handling: | Immediately after collection, incubate red top tube at 37° C for one hour. Centrifuge and, maintaining at 37° C, separate serum into a plastic vial, labeled as serum. Specimen can now be held ambient. Do not refrigerate or freeze. | ||||||||
| Stability: | 72 hours ambient. Unstable refrigerated or frozen. | ||||||||
| Standard Volume: | 5 mL serum. | ||||||||
| Minimum Volume: | 3 mL serum. | ||||||||
| Transport: | Ambient. | ||||||||
| Comments: | If cryoglobulin is present, Cryoprecipitate is tested for IgG, IgM, IgA, RF and IFE for an additional fee. Add 2 to 4 days to turnaround time.
Cryoglobulins may be present in macroglobulinemia of Waldenstrom, myeloma, chronic lymphocytic leukemia, lupus, chronic active hepatitis, and other viral infections. |
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| Rejection Criteria: | Specimen not incubated at 37° C for one hour or maintained at 37° C during collection process; refrigerated or frozen specimen. | ||||||||