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Methodology: Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)
Edit Date: 11/17/2009
Performed: Sunday, Tuesday, Thursday
Released: 1-4 days after setup at PeaceHealth Laboratories’ reference lab.
CPT Code: 80154-90
Specimen Collection Details
Collection: One 5 mL red top tube. Do not use separator tubes (SST or PST). Also acceptable: One 4 mL green top tube (sodium heparin), one 4 mL lavender top tube (EDTA), or one 4 mL grey top tube (sodium fluoride/ potassium oxalate).
Handling: Centrifuge and separate serum or plasma into a plastic vial.
Stability: 7 days ambient, 7 days refrigerated, or 2 months frozen.
Standard Volume: 2 mL serum or plasma.
Minimum Volume: 0.6 mL serum or plasma.
Transport: Refrigerated, or frozen on dry ice.
Rejection Criteria: Use of separator tube.

Reference Range:
Dose-related Range:
Anxiety 10-40 ng/mL (Dose: 1-4 mg/d)
Phobia and Panic 50-100 ng/mL (Dose: 6-9 mg/d)
Side effects will increase and anti-anxiety efficacy may decrease with higher plasma levels. Therapeutic range generally achieved with doses of 1.5-3 mg/d.

PeaceHealth Laboratories