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Alias Names: Treponema pallidum Antibody by TP-PA / STD
Methodology: Indirect Hemagglutination
Edit Date: 1/20/2010
Performed: Monday-Friday
Released: 1-4 days after setup at PeaceHealth Laboratories’ reference lab
CPT Code: 86780-90
Specimen Collection Details
Collection: One 7.5 mL serum separator tube (SST). Also acceptable: One 4.5 light green tube (PST) lithium heparin.
Handling: Centrifuge and immediately separate serum or plasma into a plastic vial.
Stability: 48 hours ambient, 14 days refrigerated, or 1 year frozen. Do not allow to thaw.
Standard Volume: 1 mL serum or plasma
Minimum Volume: 0.5 mL serum or plasma
Transport: Refrigerated.
Comments: TP-PA is a helpful diagnostic aid for the patient with a reactive reagin test, but presents with atypical signs of primary, secondary, or late syphilis. TP-PA compares favorably with the FTA test, but appears slightly less sensitive in cases of untreated early primary syphilis. In late syphilis, the agreement with FTA is 99%.

VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF.

Rejection Criteria: CSF or other body fluids; specimen thawed and refrozen.

PeaceHealth Laboratories