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| 87930:METHYLPHENIDATE (RITALIN) AND METABOLITE, URINE | |||||||||
| Alias Names: | Concerta® / Methidate® / Methylphenidate Metabolite Ritalin® | ||||||||
| Methodology: | Liquid Chromatography/Mass Spectroscopy (LC/MS) | ||||||||
| Edit Date: | 7/22/2010 | ||||||||
| Components: | Methylphenidate / Ritalinic Acid | ||||||||
| Performed: | Monday, Wednesday, Friday | ||||||||
| Released: | 24 hours after setup at PeaceHealth Laboratories’ reference lab | ||||||||
| CPT Code: | 83789-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | Random urine collected 1-6 hours post dose. | ||||||||
| Handling: | Freeze specimen within one hour of collection in a plastic bottle. | ||||||||
| Stability: | 5 months frozen at -20° C. Unstable ambient or refrigerated. | ||||||||
| Standard Volume: | 10 ml urine | ||||||||
| Minimum Volume: | 0.5 mL urine | ||||||||
| Transport: | Frozen on dry ice. | ||||||||
| Rejection Criteria: | Ambient, refrigerated, or thawing specimen. | ||||||||
| Reference Range: | |||||||||||||||||||
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Methylphenidate
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100-900 ng/mL eight hours post 25 mg oral dose to adults. Concentrations as high as 3300 ng Methylphenidate/mL have been reported in the 6-hour urine in children following a 10 mg dose.
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Ritalinic Acid
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Concentrations as high as 64000 ng Ritalinic Acid/mL have been reported in the 6-hour urine in children following a 10 mg Methylphenidate dose.
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