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93280:CAMPYLOBACTER JEJUNI ANTIBODY
Methodology:Enzyme-Linked Immunosorbent Assay (ELISA)
Edit Date:9/15/2010
Performed:Thursday
Released:1-8 days after setup at PeaceHealth Laboratories' reference lab
CPT Code:86625-90
Specimen Collection Details
Collection:One 7.5 mL serum separator tube (SST).
Handling:Allow to clot, centrifuge and separate serum into a plastic vial. Refrigerate.
Stability:7 days ambient, 2 months refrigerated, or 3 years frozen.
Standard Volume:1 mL serum
Minimum Volume:0.5 mL serum
Transport:Refrigerated.
Comments:Campylobacter jejuni is a major cause of sporadic bacterial diarrhea in the United States, with poultry the most important source of infection. Markedly elevated levels of antibodies recognizing C. jejuni typically indicate recent or ongoing infection, even though stool cultures may be negative. Neurological complications may follow C. jejuni infection; approximately 30% of Guillain-Barre cases are typically associated with recent C. jejuni infection. The basis of this association is apparently molecular mimicry between C. jejuni antigens and gangliosides of neuronal cells.
Reference Range:
<0.90