84231:IgA SUBCLASS 1 & 2

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84231:IgA SUBCLASS 1 & 2
Methodology: Nephelometry (NEPH) / Turbidimetry (TURB)
Edit Date: 11/3/2010
Components: IgA Subclass 1 / IgA Subclass 2 / IgA Total
Performed: Wednesday
Released: 24-72 hours after setup at PeaceHealth Laboratories’ reference lab
CPT Code: 82784-90 / 82787-90 x2
Specimen Collection Details
Collection: One 7.5 mL serum separator tube (SST).
Handling: Allow to clot, centrifuge and separate serum from cells into a plastic vial. Refrigerate. Provide patient’s age on requisition to allow reporting of age-specific reference ranges.
Stability: 5 days ambient, 14 days refrigerated, or 2 months frozen.
Standard Volume: 2 mL serum
Minimum Volume: 1 mL serum
Transport: Refrigerated
Comments: Approximately 10 to 15% of serum immunoglobulin is IgA, which contains 10% carbohydrate, and has a half-life of 6 days. About 10 to 15% of IgA in serum in polymeric, particularly IgA2, which is more resistant to destruction by some pathogenic bacteria than is IgA1. This test Identifies and quantitates IgA subclasses 1 and 2.

Reference Range:
IgA Subclass ! 98.6-353.1 mg/dL
IgA Subclass 2 11.6-78.5 mg/dL
IgA Total
< 2 months 2 – 43 mg/dL
< 6 months 3 – 66 mg/dL
< 10 months 7 – 66 mg/dL
< 13 months 12 – 75 mg/dL
< 4 years 24 – 121 mg/dL
< 7 years 33 – 235 mg/dL
< 10 years 41 – 368 mg/dL
< 12 years 64 – 246 mg/dL
< 14 years 70 – 432 mg/dL
< 16 years 57 – 300 mg/dL
≥ 16 years 81 – 463 mg/dL

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