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41160:ALPHA FETOPROTEIN, AMNIOTIC FLUID (AFAFP)
Methodology:Chemiluminescent Immunoassay (CLIA)
Edit Date:6/11/2010
Performed:Monday-Friday
Released:Same day as tested
CPT Code:82106
Specimen Collection Details
Collection:Amniotic fluid in a clean, unused container. Include patient's gestational age in weeks.
Handling:Refrigerate. Do not freeze.
Stability:7 days refrigerated.
Standard Volume:2 mL amniotic fluid.
Minimum Volume:0.5 mL amniotic fluid.
Transport:Refrigerated.
Comments:Specimen contaminated with red cells will be tested to determine if they are fetal or adult. Visibly bloody specimen will be examined for fetal RBCs by Kleihauer-Betke technique or fetal Hgb methods. Amniotic fluid specimen contaminated with fetal blood may exhibit abnormally high AFP values. Patients with an amniotic fluid AFP ≥ 2 MOM are at increased risk for a neural tube defect or ventral wall defect and should have amniotic fluid acetylcholinesterase determined. The ordering physician will be notified of the abnormal results and a request for acetylcholinesterase can be made at that time.
See patient report. Ranges are based on the weeks of gestation.