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Alias Names: Anti-HBc
Methodology: Chemiluminescence (CL)
Edit Date: 11/14/2009
Performed: Daily
Released: Same day as tested
CPT Code: 86704
Specimen Collection Details
Collection: One 7.5 mL serum separator tube (SST). Also acceptable:One 5 mL red top tube. Patients need not be fasting and no special preparations are necessary.
Handling: Allow to clot, centrifuge and separate serum from cells immediately. Refrigerate. Freeze if specimen cannot be assayed within 48 hours. Allow no more than two freeze/thaw cycles. If multiple tests are ordered, send separate specimen for this test.
Standard Volume: 2 mL serum.
Minimum Volume: 1 mL serum.
Transport: Refrigerated; or if frozen, on dry ice.
Comments: Used to monitor the progress of hepatitis B viral infection. Anti-HBc is found in serum shortly after appearance of hepatitis B surface antigen (HBsAG) in acute hepatitis B and will persist after the disappearance of HBsAG and before the appearance of detectable antibody to HBsAG (Anti-HBs).
Rejection Criteria: Gross hemolysis; gross lipemia; heat-inactivated specimens; specimen received in laboratory more than 48 hours after collection



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