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| 58760:THYROGLOBULIN ANTIBODY (ANTI-TG) | |||||||||
| Alias Names: | Thyroid Autoantibody | ||||||||
| Methodology: | Chemiluminescent Immunoassay (CLIA) | ||||||||
| Edit Date: | 6/11/2010 | ||||||||
| Performed: | Daily | ||||||||
| Released: | Same day as tested | ||||||||
| CPT Code: | 86800 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | One 7.5 mL serum separator tube (SST). Also acceptable: One 5 mL red top tube. | ||||||||
| Handling: | Allow to clot, centrifuge and separate serum from cells. Refrigerate. | ||||||||
| Stability: | 2 hours ambient, 7 days refrigerated, or 6 months frozen. Allow no more than one freeze/thaw cycle. | ||||||||
| Standard Volume: | 1 mL serum. | ||||||||
| Minimum Volume: | 0.5 mL serum. | ||||||||
| Transport: | Refrigerated; if frozen, on dry ice. | ||||||||
| Rejection Criteria: | Gross hemolysis or lipemia; specimen frozen/thawed more than once. | ||||||||
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0-40 IU/mL |
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| Interpretive Note: Elevated values of thyroglobulin antibodies are seen in Hashimoto’s disease, primary hypothyroidism and Grave’s disease. While not diagnostic, the detection of thyroglobulin antibodies can aid in predicting progression of clinical thyroiditis, in further substantiating thyroid disease in patients with non-thyroidal illness and in predicting postpartum thyroiditis. | |||||||||||||||||||