 Print View Attached Docs: |
|||||||||
| 82581:COLLAGEN CROSS-LINKED N-TELOPEPTIDE | |||||||||
| Alias Names: | URINE N-TELOPEPTIDE, BONE RESORPTION, NTX | ||||||||
| Methodology: | Chemiluminescent Immunoassay (CLIA) | ||||||||
| Edit Date: | 3/29/2007 | ||||||||
| Performed: | Tuesday-Saturday | ||||||||
| Released: | 1-4 days after setup at PeaceHealth Laboratories’ reference lab. | ||||||||
| CPT Code: | 82523-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | Discard first morning specimen. Second morning urine voided into a sterile plastic container. Do not add preservatives. Also acceptable: 24-hour urine. Refrigerate during and after collection. | ||||||||
| Handling: | Refrigerate a 1 mL aliquot from a well-mixed collection. | ||||||||
| Stability: | 24 hours ambient, 7 days refrigerated, or 2 years frozen. | ||||||||
| Standard Volume: | 1 mL urine. | ||||||||
| Minimum Volume: | 0.5 mL urine. | ||||||||
| Transport: | Refrigerated. | ||||||||
| Comments: | For monitoring therapy, a baseline specimen should be collected prior to initiation of therapy. Subsequent specimens for comparison should be collected at the same time of day as the baseline specimen. | ||||||||
| Rejection Criteria: | Acidified specimen; specimen contaminated with blood; extensive hemolysis. | ||||||||
| Reference Range: | |||||||||||||||||||
| AGE | MALE | FEMALE | |||||||||||||||||
| 7-9 years | 167-578 nM BCE/mM creatinine | 201-626 nM BCE/mM creatinine | |||||||||||||||||
| 10-12 years | 152-505 nM BCE/mM creatinine | 173-728 nM BCE/mM creatinine | |||||||||||||||||
| 13-15 years | 103-776 nM BCE/mM creatinine | 38-515 nM BCE/mM creatinine | |||||||||||||||||
| 16-17 years | 34-313 nM BCE/mM creatinine | 20-144 nM BCE/mM creatinine | |||||||||||||||||
| 18 years and older | 21-83 nM BCE/mM creatinine | ||||||||||||||||||
| Premenopausal | 17-94 nM BCE/mM creatinine | ||||||||||||||||||
| Postmenopausal | 26-124 nM BCE/mM creatinine | ||||||||||||||||||
| A decrease of 30-40% from the NTx baseline after three months of therapy is a typical response to anti-resorptive therapy.
NTx Units (NTx=Cross-linked N-telopeptide of Type I Collagen) = nM BCE/mM creatinine (BCE=Bone Collagen Equivalent) |
|||||||||||||||||||