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| 92840:BONE SPECIFIC ALKALINE PHOSPHATASE | |||||||||
| Alias Names: | BSAP | ||||||||
| Methodology: | Chemiluminescent Immunoassay (CLIA) | ||||||||
| Edit Date: | 5/18/2009 | ||||||||
| Performed: | Daily | ||||||||
| Released: | 24-48 hours after setup at PeaceHealth Laboratories’ reference lab. | ||||||||
| CPT Code: | 84080-90 | ||||||||
| Specimen Collection Details | |||||||||
| Collection: | One 7.5 mL serum separator tube (SST). Also acceptable: One 4 mL green top tube (heparin). | ||||||||
| Handling: | Allow to clot, centrifuge and separate serum or plasma from cells and pour into plastic vial. Freeze. | ||||||||
| Stability: | After separation from cells: 2 hours ambient, 48 hours refrigerated, or 1 year frozen. | ||||||||
| Standard Volume: | 0.5 mL serum or plasma. | ||||||||
| Minimum Volume: | 0.3 mL serum or plasma. | ||||||||
| Transport: | Frozen on dry ice. | ||||||||
| Rejection Criteria: | Grossl hemolysis. | ||||||||
| AGE | MALE | FEMALE | |||||||||||||||||
| 7-9 years | 48.6-140.4 µg/L | 36.3-159.4 µg/L | |||||||||||||||||
| 10-12 years | 48.8-155.5 µg/L | 44.2-163.3 µg/L | |||||||||||||||||
| 13-15 years | 27.8-210.9 µg/L | 14.8-136.2 µg/L | |||||||||||||||||
| 16-17 years | 15.3-126.8 µg/L | 10.5-44.8 µg/L | |||||||||||||||||
| 25 years and older | 6.5-20.1 µg/L | ||||||||||||||||||
| Premenopausal | 4.5-16.9 µg/L | ||||||||||||||||||
| Postmenopausal | 7.0-22.4 µg/L | ||||||||||||||||||
| Note: Reference intervals have not been established for children younger than 7 years or males 18-24 years of age.
Liver alkaline phosphatase can affect the measurement of bone specific alkaline phosphatase in this assay. Each 100 U/L of liver alkaline phosphatase contributes an additional 2.5 to 5.8 µg/L to the bone specific alkaline phosphatase result. |
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