82450:CLOMIPRAMINE (ANAFRANIL) and METABOLITE
Author PeaceHealth Laboratories
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| Alias Names: |
Anafranil |
| Methodology: |
High Performance Liquid Chromatography/Tandem Mass Spectrometry (HPLC/MS/MS) |
| Edit Date: |
11/16/2010 |
| Performed: |
Daily |
| Released: |
24-48 hours after setup at PeaceHealth Laboratories’ reference lab. |
| CPT Code: |
82492-90 |
| Specimen Collection Details |
| Collection: |
One 5 mL red top tube. Do not use separator tube (SST or PST). Also acceptable: One 4 mL green top tube (sodium heparin), 4 mL lavender top tube (EDTA), or 4 mL grey top tube (sodium fluoride/potassium oxalate). |
| Handling: |
Allow to clot, centrifuge and separate serum or plasma from cells and pour into a plastic vial. Refrigerate. |
| Stability: |
5 days ambient, 14 dyas refrigerated, or 6 months frozen. |
| Standard Volume: |
2 mL serum or plasma. |
| Minimum Volume: |
0.8 mL serum or plasma. |
| Transport: |
Refrigerated. |
| Rejection Criteria: |
Use of SST or PST. |
|
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Total Clomipramine and Desmethyl: |
220-500 ng/mL |
|
Toxic: |
>900 ng/mL |
| Plasma concentrations vary widely among patients. The therapeutic range listed relates to the antidepressant characteristics of the drug. A therapeutic range for treating obsessive-compulsive disorder is not well defined.
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