40785:HEPATITIS COMPREHENSIVE A, B & C PANEL WITH REFLEX, IF INDICATED

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40785:HEPATITIS COMPREHENSIVE A, B & C PANEL WITH REFLEX, IF INDICATED
Methodology: See Individual Components
Edit Date: 11/16/2009
Components: Hepatitis A Antibody, Total (Anti-HAV, IgG & IgM) / Hepatitis B Core Antibody Total, IgG and IgM (Anti-HBc Total) / Hepatitis B Surface Antibody (Anti-HBs) / Hepatitis B Surface Antigen (HBsAG) / Hepatitis C Virus Antibody (Anti-HCV, IgG amd IgM) / Hepatitis A Antibody, IgM (Anti-HAV, IgM), if indicated; Hepatitis Be Antibody (Anti-HBe), if indicated / Hepatitis Be Antigen (HBeAG), if indicated / Hepatitis B Core Antibody, IgM (Anti-HBc, IgM), if indicated
NOTE: Hepatitis A Antibody, IgM, Hepatitis Be Antibody, Hepatitis Be Antigen, Hepatitis B Core Antibody, IgM will be performed and charged if indicated. While these tests reflect our recommendations for testing, all tests included in this panel may be ordered individually or in any combination.
Performed: Daily
Released: Same day as tested
CPT Code: 86704 / 86706 / 86708 / 86803 / 87340 / (86708 if indicated) / (86707 if indicated) / (87350 if indicated) / (86705 if indicated)
Specimen Collection Details
Collection: One 7.5 mL serum separator tube (SST). Also acceptable: One 5 mL red top tube. Patients need not be fasting and no special preparations are necessary.
Handling: Allow to clot, centrifuge and immediately separate serum from cells. Refrigerate. Freeze if specimen will not be assayed within 48 hours. Avoid repeated freeze/thaw cycles. If other testing is ordered, send a separate specimen for this test.
Standard Volume: 3 mL serum.
Minimum Volume: 2 mL serum.
Transport: Refrigerated, or frozen on dry ice.
Comments: Useful for:
1) The differential diagnosis of recent acute hepatitis.
2) Determining if an individual has been infected following exposure to an unknown type of hepatitis.
3) Obtaining baseline serologic markers of an individual exposed to a source with an unknown type of hepatitis.
4) Determining immunity of hepatitis A and B viral infections.
Rejection Criteria: Gross hemolysis; gross lipemia; heat-inactivated specimens; refrigerated specimen received in laboratory more than 48 hours after collection.

Hepatitis Comprehensive A, B & C Panel Interpretation

See individual components.

Anti-HAV Total (IgG and IgM) Anti-HAV IgM Anti-HCV HBsAG Anti-HBc Total Anti-HBc IgM Anti-HBs HBeAG Anti-HBe Interpretation
not done + + + not done not done Acute Type B Hepatitis
not done + + + Chronic Type B Hepatitis, infectious state (consider ordering HBV-DNA)
not done + + + Chronic Type B Hepatitis, carrier state
+ + not done not done Past Type B Hepatitis infection with immunity
+ not done not done not done Past Type A Hepatitis infection with immunity
+ + not done not done not done Acute Type A Hepatitis
+ not done not done not done Exposure to Type C Hepatitis*

*If Anti-HCV is positive, recommend performing HCV RNA Quantitative by PCR (40738) to determine if patient is infected with HCV.

PeaceHealth Laboratories