90825:BUPROPION

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90825:BUPROPION
Alias Names: Wellbutrin® / Zyban®
Methodology: High-Performance Liquid Chromatography (HPLC)
Edit Date: 6/11/2010
Performed: Monday, Thursday
Released: 1-5 days after setup at PeaceHealth Laboratories’ reference lab.
CPT Code: 80299-90
Specimen Collection Details
Collection: One 5 mL red top tube. Do not use serum separator tube (SST) or plasma separator tube (PST. Also acceptable: One 4 mL lavender top tube (EDTA), 4 mL green top tube (sodium heparin), or 4 mL grey top tube (sodium fluoride/potassium oxalate).
Handling: Allow to clot, centrifuge and separate serum or plasma from cells into a plastic vial. Freeze within 2 hours of collection. Critical frozen. Send separate specimen if multiple tests are ordered.
Stability: 30 days frozen. Unstable ambient or refrigerated.
Standard Volume: 2.5 mL serum or plasma.
Minimum Volume: 1.5 mL serum or plasma.
Transport: Frozen, on dry ice.
Rejection Criteria: Use of SST or PST; thawed, ambient, or refrigerated specimen.
This test may require insurance company prior authorization before ordering.
Please check the prior authorization list
.
Failure to gain preauthorization may result in denial of coverage.

The therapeutic range is not well established. Patient response appears to improve with concentrations between 50 and 100 ng/mL. Levels below 25 ng/mL may have no effect. Poor response and increased toxicity have been reported at concentrations above 100 ng/mL.