80480:ALPRAZOLAM (XANAX) LEVEL
Author PeaceHealth Laboratories
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| Methodology: |
Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS) |
| Edit Date: |
11/17/2009 |
| Performed: |
Sunday, Tuesday, Thursday |
| Released: |
1-4 days after setup at PeaceHealth Laboratories’ reference lab. |
| CPT Code: |
80154-90 |
| Specimen Collection Details |
| Collection: |
One 5 mL red top tube. Do not use separator tubes (SST or PST). Also acceptable: One 4 mL green top tube (sodium heparin), one 4 mL lavender top tube (EDTA), or one 4 mL grey top tube (sodium fluoride/ potassium oxalate). |
| Handling: |
Centrifuge and separate serum or plasma into a plastic vial. |
| Stability: |
7 days ambient, 7 days refrigerated, or 2 months frozen. |
| Standard Volume: |
2 mL serum or plasma. |
| Minimum Volume: |
0.6 mL serum or plasma. |
| Transport: |
Refrigerated, or frozen on dry ice. |
| Rejection Criteria: |
Use of separator tube. |
| Dose-related Range: |
|
Anxiety |
10-40 ng/mL (Dose: 1-4 mg/d) |
|
Phobia and Panic |
50-100 ng/mL (Dose: 6-9 mg/d) |
| Side effects will increase and anti-anxiety efficacy may decrease with higher plasma levels. Therapeutic range generally achieved with doses of 1.5-3 mg/d.
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