82180:CHLORDIAZEPOXIDE (LIBRIUM) LEVEL

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82180:CHLORDIAZEPOXIDE (LIBRIUM) LEVEL
Methodology: High Performance Liquid Chromatography (HPLC)
Edit Date: 11/19/2009
Components: Librium / Nordiazepam
Performed: Monday, Thursday
Released: 1-4 days after setup at PeaceHealth Laboratories’ reference lab.
CPT Code: 80154-90 x2
Specimen Collection Details
Collection: One 5 mL red top tube. Also acceptable: One 4 mL green top tube (heparin), one 4 mL lavender top tube (EDTA), or one 4 mL grey top tube (sodium fluoride/potassium oxalate). Do not use a serum or plasma separator tube (SST or PST). Protect from light.
Handling: Protect from light. Centrifuge and separate serum or plasma into a plastic vial. Wrap in foil and freeze within 4 hours of collection. If other tests are ordered send a separate specimen for this test.
Stability: 4 hours ambient, 24 hours refrigerated, or 5 days frozen.
Standard Volume: 2 mL serum or plasma.
Minimum Volume: 1 mL serum or plasma.
Transport: Frozen on dry ice.

Reference Range:
Dose-related range:
Librium 0.5-3.0 µg/mL – based on dosages up to 100 mg.
Toxic: >5.0 µg/mL
Nordiazepam 0.06-1.80 µg/mL – Based on normal dosages.
Toxic: >2.5 µg/mL