92220:VENLAFAXINE (EFFEXOR®) LEVEL

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92220:VENLAFAXINE (EFFEXOR®) LEVEL
Alias Names: Desmethylvenla faxine
Methodology: High Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV)
Edit Date: 2/8/2010
Performed: Daily
Released: 24-48 hours after setup at PeaceHealth Laboratories’ reference lab
CPT Code: 82492-90
Specimen Collection Details
Collection: One 5 mL red top tube. Do not use serum separator tube (SST). NOTE: Trough levels are most reproducible.
Handling: Allow to clot, centrifuge and separate serum into a plastic vial.
Stability: 72 hours ambient. Refrigerate or freeze for longer storage.
Standard Volume: 3 mL serum
Minimum Volume: 0.6 mL serum
Transport: Refrigerated.
Rejection Criteria: Use of SST.

Reference Range:
Report Limit: 10 ng/mL

Reference ranges for venlafaxine and desmethylvenlafaxine have not been established. Expected concentrations for venlafaxine are 100-500 ng/mL with desmethylvenlafaxine concentrations of 200-400 ng/mL. Toxic concentrations have not been established.