87930:METHYLPHENIDATE (RITALIN) AND METABOLITE, URINE

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87930:METHYLPHENIDATE (RITALIN) AND METABOLITE, URINE
Alias Names: Concerta® / Methidate® / Methylphenidate Metabolite Ritalin®
Methodology: Liquid Chromatography/Mass Spectroscopy (LC/MS)
Edit Date: 7/22/2010
Components: Methylphenidate / Ritalinic Acid
Performed: Monday, Wednesday, Friday
Released: 24 hours after setup at PeaceHealth Laboratories’ reference lab
CPT Code: 83789-90
Specimen Collection Details
Collection: Random urine collected 1-6 hours post dose.
Handling: Freeze specimen within one hour of collection in a plastic bottle.
Stability: 5 months frozen at -20° C. Unstable ambient or refrigerated.
Standard Volume: 10 ml urine
Minimum Volume: 0.5 mL urine
Transport: Frozen on dry ice.
Rejection Criteria: Ambient, refrigerated, or thawing specimen.

Reference Range:
Methylphenidate
100-900 ng/mL eight hours post 25 mg oral dose to adults. Concentrations as high as 3300 ng Methylphenidate/mL have been reported in the 6-hour urine in children following a 10 mg dose.
Ritalinic Acid
Concentrations as high as 64000 ng Ritalinic Acid/mL have been reported in the 6-hour urine in children following a 10 mg Methylphenidate dose.