84020:FLUOXETINE (PROZAC) AND METABOLITE

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84020:FLUOXETINE (PROZAC) AND METABOLITE
Alias Names: Norfluoxetine
Methodology: High Performance Liquid Chromatography (HPLC)
Edit Date: 6/11/2010
Performed: Monday, Wednesday, Friday
Released: 1-4 days after setup at PeaceHealth Laboratories’ reference lab.
CPT Code: 80299-90 x2
Specimen Collection Details
Collection: One 5 mL red top tube. Do not use serum or plasma separator tube, SST or PST. Also acceptable: One 4 mL green top tube (sodium heparin), 4 mL lavender top tube (EDTA), or 4 mL grey top tube (potassium oxalate/sodium fluoride).
Handling: Allow to clot, centrifuge and separate serum or plasma from cells into a plastic vial. Refrigerate.
Stability: 12 hours ambient, 5 days refrigerated, or 1 month frozen.
Standard Volume: 2 mL serum or plasma.
Minimum Volume: 0.8 mL serum or plasma.
Transport: Refrigerated.
Comments: Fluoxetine metabolizes into norfluoxetine. Both levels are provided on the report. Dose related ranges for fluoxeline/norfluoxetine are based on a 20-60 mg dose/day.
Rejection Criteria: Use of SST or PST.
This test may require insurance company prior authorization before ordering.
Please check the prior authorization list
.
Failure to gain preauthorization may result in denial of coverage.

Dose-related range:
Fluoxetine 50-480 ng/mL
NorFluoxetine 50-450 ng/mL