25280:D-DIMER, QUANTITATIVE

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25280:D-DIMER, QUANTITATIVE
Alias Names: Fibrin Split Poducts (FDP), D-Dimer / FDP, D-Dimer / Fibrin D-Dimer
Methodology: Mechanical Coagulation Analyzer / Immunoturbidometric Assay
Edit Date: 3/17/2009
Performed: Daily
Released: 2 hours
CPT Code: 85379
Specimen Collection Details
Collection: One 4.5 mL light blue top tube (sodium citrate). Collect by careful venipuncture to avoid tissue contamination or hemolysis. Do not use needles smaller than 23 gauge. Fill tube to maximum draw, at least 90% full. Mix by gentle inversion.
Handling: Refrigerate and keep capped in the original tube if specimen will be received at the laboratory within 8 hours. If not, centrifuge to produce platelet-poor plasma. Transfer to a plastic tube and freeze. Label with patient name, I.D. number, test, and ‘citrate.’ Send to the laboratory within one month.
Stability: 4 hours ambient, 8 hours refrigerated, or 7 days frozen.
Standard Volume: 5 mL whole blood or 2 mL plasma.
Minimum Volume: 2 mL whole blood or 0.5 mL plasma.
Transport: Original tube refrigerated if received in laboratory within 8 hours of collection; citrated plasma frozen on dry ice.
Rejection Criteria: Serum; visible fibrin; moderate to marked hemolysis.

Reference Range:
0-0.50 µg/mL FEU

This assay is optimized for sensitivity to low levels of D-Dimer. Elevated levels suggest fibrinolysis of intravascular thrombin, causes of which include PE, DVT, DIC, post-surgical wound healing, and trauma. A normal D-Dimer level (<0.5 ug/mL) indicates a very low probability of intravascular thrombosis.

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